News
…Rare Disease Day and Rare Disease Research within the Warren Center
Rare Disease Day takes place annually on the last day of February. Rare Disease Day’s goal is to raise awareness amongst the general public and decision-makers about rare diseases and their impact on patients. Warren Center researchers have a rich history in rare disease therapeutic research and a few examples are summarized below.…
College of Science Faculty Awarded Support from CTSI Molecular Therapeutics Program
Notre Dame Faculty from the Departments of Chemistry & Biochemistry and Biological Sciences have been awarded a grant from the Indiana Clinical and Translational Sciences Institute (CTSI).
Bradley Smith, Emil T. Hofman Professor of Chemistry & Biochemistry and a researcher in the Warren Family Research Center for Drug Discovery and Development…
Warren Center Researcher Selected for the National Institutes of Health Neurotherapeutics Program
Notre Dame's Richard Taylor, Interim Director of the Warren Family Research Center for Drug Discovery and Development and Professor of Chemistry & Biochemistry has been selected to participate in a National Institutes of Health training program, “Neurotherapeutics Discovery and Development for Academic Scientists
…New avenues found for treatment of pathogen behind diseases including fasciitis, toxic shock syndrome
One bacterial pathogen is responsible for a range of diseases, from pharyngitis and impetigo to more severe diagnoses such as toxic shock syndrome and necrotizing fasciitis (flesh eating disease), a serious bacterial skin infection that spreads quickly and kills the body’s soft tissue. The pathogen, known as Group A Streptococcus, remains a global health burden with an estimated 700 million cases reported annually, and more than half a million deaths due to severe infections.
New finding offers hope for diabetic wound healing
University of Notre Dame researchers have discovered a compound that accelerates diabetic wound healing, which may open the door to new treatment strategies.
New Notre Dame-Eli Lilly & Co. Faculty Fellowship Program in Drug Discovery Announced
Faculty researchers with an interest in the drug discovery process from across the University are invited to apply to spend a period of at least two to three months embedded within the chemistry program at Eli Lilly & Co. in Indianapolis, Indiana.
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Warren Family Research Center for Drug Discovery and Development partners with Retrophin and the Grace Wilsey Foundation
The Warren Family Research Center for Drug Discovery and Development at the University of Notre Dame has established a research collaboration with Retrophin, Inc. and the Grace Wilsey Foundation to focus on developing treatment for NGLY1 deficiency. …
CTSI Funding Opportunity for Early Stage Commercialization in Diagnostics and Therapeutics Development
SUBMISSION DEADLINE - THURSDAY, OCTOBER 01, 2015 (5:00 PM).
A common critical gap in commercialization of technologies originating from the academic labs is the funding necessary to develop a robust commercialization relevant data package to reduce the risk of investment in early stage technologies. The Indiana CTSI and Indiana University School of Medicine through the office of the Associate Dean for Entrepreneurship and its Industry Collaboration Portal (ICP), are partnering with the newly created Indiana Center for Biomedical Innovation (ICBI) at IU Health to help fill this critical gap through a new support program, Technology Enhancement Awards (TEA), for early stage technologies. The technology may already reside in a start-up company or a clear plan exists to place it into a start-up. The New Program will partner with the highly successful SPARK program at Stanford University.…
New Funding Opportunity to Support Pre-clinical Assays
Drug Development Services through the Molecular Therapeutics Program
SUBMISSION DEADLINE: October 15, 2015
The Molecular Therapeutics Program, a part of the Indiana Clinical and Translational Sciences Institute, has established a service agreement with Covance, Inc. to support early-stage drug discovery within CTSI partners: Indiana University, Purdue University, and the University of Notre Dame. The Molecular Therapeutic Program (MTP) will support early-stage drug development studies through services provided by Covance Inc. and Quintiles Biosciences, two contract research organizations that provide pharmaceutical development services. Small grants are now available to help support a list of services available: …
Stahelin named recipient of Navari gift
Robert V. Stahelin, Ph. D., associate professor of biochemistry and molecular biology at Indiana University School of Medicine-South Bend (IUSM-SB), adjunct faculty in the Department of Chemistry & Biochemistry has been awarded the Navari Family Endowed Chair…
Helquist and Wiest awarded APMRF grant
WFRCDD Investigators and Professors of Chemistry & Biochemistry Paul Helquist and Olaf Wiest have been awarded a $100,000 grant from the Ara Parseghian Medical Research Foundation for "Design and Synthesis of Small Molecule Agents for Studies and Treatment of NPC Disease". Much of the work, which includes a group of international collaborators, will be carried out in the Chemical Synthesis and Drug Discovery Facility.…
Three questions with Rich Taylor: Alzheimer's and Brain Awareness Month
June is Alzheimer’s and Brain Awareness Month, which seemed a particularly apt time to talk with Rich Taylor, a University of Notre Dame researcher whose research focuses on the discovery and development of new therapeutic leads for the treatment of unmet clinical needs in a number of diseases, including Alzheimer’s. Taylor is associate vice president for research, professor of chemistry and biochemistry and interim director of the Warren Family Research Center for Drug Discovery and Development.
CO-ADD Offers Antibiotic ESKAPE Screens
The Community forOpen Antimicrobial Drug Discovery (CO-ADD) is a Wellcome Trust funded, non-for-profit, openframework for discovery and development of new therapies against multidrug-resistant (MDR) bacteria (www.co-add.org) based at The University of Queensland in Australia.
CO-ADD will perform primary antibacterial screening for academic research groups as a free service and makes no claims on results or IP.…
Spotlight: Rich Taylor
Rich Taylor, a member of the University of Notre Dame faculty since 1995, is a professor of chemistry and biochemistry in the College of Science. Taylor, who also serves as associate vice president for research at the University, has recently been appointed as interim director of the Warren Family Research Center for Drug Discovery and Development. Read more...
Funding Opportunity through Indiana CTSI Molecular Therapeutics Program
Molecular Therapeutics Program Early Stage Drug Discovery Support
Seed funding, up to $10,000, and advice is available for researchers seeking to develop early stage drug discovery projects.
SUBMISSION DEADLINE - July 1, 2015
The Molecular Therapeutics Program, a part of the Indiana Clinical and Translational Sciences Institute, seeks applications for a competitive program that will provide funds and essential consultation to support the early stage development of therapeutics. This opportunity is provided in concert with the newly established Indiana Drug Discovery Alliance (IDDA), a clearinghouse for drug discovery and development resources at the Indiana-CTSI member institutions of Indiana University, Purdue University and the University of Notre Dame.
Warren Family Center initiates creation of international research team in collaboration with the Grace Wilsey Foundation.
Warren Family Center initiated the creation of an international team of researchers focused on the search for small molecule therapeutics for NGLY1 deficiency in collaboration with the Grace Wilsey Foundation.…
Researchers identify molecular mechanism responsible for making malaria parasites drug-resistant
University of Notre Dame researchers led an international team to identify a molecular mechanism responsible for making malaria parasites resistant to artemisinins, the leading class of antimalarial drugs.
According to the World Health Organization’s 2014 World Malaria Report, there are an estimated 198 million cases of malaria worldwide with 3.3 billion people at risk for contracting the infection. Although the impact of malaria is still significant, the statistics reflect a considerable reduction in the global malaria burden. Since 2010, disease transmission has been reduced by 30 percent and mortality due to malaria has decreased by almost half.
Warren Family Center hosted a visitor from Novartis Pharmaceutical Corporation
Warren Family Center hosted a visitors from Novartis Pharmaceutical Corporation including Susan Giacalone (Area Scientific Associate Director- Field Medical MSL, Rare Diseases), Julio Fernandez (Field Medical National Director, Rare Diseases), John Murry, (Regional Scientific Director), Beth Ostergard Stillwell (Oncology Regional Scientific Director).…
Warren Family Center hosted a visit from Eli Lilly President and CEO, Dr. John Lechleiter and Senior Director, Dr. Jay McGill.
Warren Family Center hosted a visit from Eli Lilly President and CEO, Dr. John Lechleiter and Senior Director, Dr. Jay McGill.…